Chances are you had never heard of MPDs - until you or someone in your family was diagnosed.
Myeloproliferative disorders (also called myeloproliferative neoplasms) are a spectrum of disorders, ranging from mild to more aggressive conditions. There are three main types of MPDs called essential thrombocythaemia, polycythaemia vera and myelofibrosis. MPDs are rare: people with MPDs number just one in 100,000. And they can strike people of any age, even children. The three MPDs are distinct diseases but they have one feature in common – they affect the levels of blood cells produced in our bodies.
Full blood counts show how your bone marrow is working.
People with MPDs can have high or sometimes low blood cell counts.
We don't know exactly what causes MPDs - but genetic mutations seem to play a role.
Essential thrombocythaemia, polycythaemia vera and myelofibrosis are the three most common MPDs.
ET causes a raised platelet count in people who have this disorder.
Myelofibrosis causes scar tissue to grow inside the bone marrow.
If you have PV your bone marrow produces too many red blood cells.
Terms can be confusing. Our glossary can help improve your understanding.