Allopurinol is a drug that is used to treat gout.
Gout is a painful condition caused by uric acid crystals in your body. Gout is a side effect of MPDs. It’s also unfortunately a side effect of many treatments used to treat MPDs, including hydroxycarbamide, anagrelide and interferon treatment.
This painful condition can be controlled in several ways:
Your haematologist may sometimes prescribe allopurinol as a premedication for patients who are just starting therapies for their MPD. They may then stop taking allopurinol as their blood counts normalise. Patients who have had gout, and in particular more than one episode, often take this medication over the long term.
Allopurinol often causes side effects of skin rash and a metallic taste in your mouth.
It is best to avoid taking allopurinol in pregnancy.